Some developments in biomedicine have human rights implications that give rise to specific ethical concerns and make them particularly challenging.

Public debate In this document and in Article 28 of the Oviedo Convention the overarching concept of ‘public debate’ is used to describe discursive interactions in the public sphere (that is, not in a professional context) through which individuals and groups may identify, explore and resolve their different interests in matters that affect (or potentially affect) them all. can be particularly important around biomedical developments that have a profound impact on society and individuals, developments that may fall outside existing regulatory frameworks, and developments that may entail unknown risks or have an unpredictable effect on society, or disproportionately affect certain groups.